منابع مشابه
Leading article Cholesterol crystallisation in bile
Cholesterol gallstones occur when at least three simultaneous defects are present: (i) cholesterol supersaturation of bile with formation of cholesterol-rich unstable vesicles; (ii) accelerated crystallisation of cholesterol in bile owing to a defect of crystallisation inhibiting or an abundance of crystallisation promoting factors; and (iii) prolonged bile stasis due to decreased gall bladder ...
متن کاملLeading article Cholesterol crystallisation in bile
Cholesterol gallstones occur when at least three simultaneous defects are present: (i) cholesterol supersaturation of bile with formation of cholesterol-rich unstable vesicles; (ii) accelerated crystallisation of cholesterol in bile owing to a defect of crystallisation inhibiting or an abundance of crystallisation promoting factors; and (iii) prolonged bile stasis due to decreased gall bladder ...
متن کاملFatty acid bile acid conjugates (FABACs)--new molecules for the prevention of cholesterol crystallisation in bile.
BACKGROUND Cholesterol gall stones are a frequent disease for which at present surgery is the usual therapy. Despite the importance of bile acids it has become evident that phospholipids are the main cholesterol solubilisers in bile. Even phospholipid components, such as fatty acids, have anticrystallising activity. AIM To synthesise fatty acid bile acid conjugates (FABACs) and study their ef...
متن کاملBiliary aminopeptidase-N and the cholesterol crystallisation defect in cholelithiasis.
Several biliary proteins have cholesterol crystallisation promoting activity. One of these glycoproteins is aminopeptidase-N, a canalicular ectoenzyme. This study attempted to localise aminopeptidase-N along the biliary tree, to assess its concentration in a series of 98 patients subjected to abdominal surgery, 40 of them without gall stones, and to correlate its concentration with cholesterol ...
متن کاملIi. Bile Cholesterol
Under uniform diet conditions the normal bile fistula dog will eliminate pretty constant amounts of cholesterol-about 0.5 to 1.0 mg. cholesterol per kilo per 24 hours. Diets rich in cholesterol (egg yolk) will raise the cholesterol output in the bile but compared to the diet intake (1.5 gm. cholesterol) the output increase in the bile is trivial (5-15 mg.). Calves' brains in the diet are inert....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gut
سال: 1997
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gut.41.2.138